IMPLEMENTING UNIVERSAL LYNCH SYNDROME SCREENING (IMPULSS): PROTOCOL FOR A MULTI-SITE STUDY TO IDENTIFY STRATEGIES TO IMPLEMENT, ADAPT, AND SUSTAIN GENOMIC MEDICINE PROGRAMS IN DIFFERENT ORGANIZATIONAL CONTEXTS

Abstract Background Systematic screening of all colorectal tumors for Lynch Syndrome (LS) has been recommended since 2009.Currently, implementation of LS screening in healthcare systems remains variable, likely because LS screening involves the complex coordination of multiple departments and individuals across the healthcare system.Our specific ai

Series of multivalent α-l-fucoside containing glycoclusters and variously decorated l-fucosides were synthesized to find potential inhibitors of fucose-specific lectins and study the ORG SPELT FLOUR structure-binding affinity relationships.Tri- and tetravalent fucoclusters were built using copper-mediated azide-alkyne click chemistry.Series of

The article extends beyond conventional models and indicators by initially attempting to Desk Parts capture the complex effects of green technological innovations and changes in natural resource extraction and natural gas production on a novel environmental quality indicator (CO, intensity, CO2ei) for the BRICS countries from 1990 to 2020.The empir

Background and Objective: Total hip arthroplasty [THA] is frequently performed in Egypt for patients with degenerative joint disease.This procedure is performed under general anaesthesia and is associated with severe postoperative pain.Pregabalin has been described as an effective adjuvant for spinal anaesthesia.However, its optimum dose has not be

It seems common to believe that measures reported Safety Helmets by participants in the behavioral sciences attain ordinal but not interval status.We consider three different measurement situations: Where one value is obtained from each of a number of respondents; where the measure is formed from combining other measures; and where the measure is o